The Django framework
Object-relational mapper
Define your data models entirely in Python. You get a rich, dynamic database-access API for free — but you can still write SQL if needed.
URL dispatcher
Design pretty, cruft-free URLs with no framework-specific limitations. Be as flexible as you like.
Template system
Use Django's powerful and extensible template language to separate design, content and Python code.
Cache system
Hook into memcached or other cache frameworks for super caching — as granularly as you need.
Automatic admin interface
Save yourself the tedious work of creating interfaces for people to add and update content. Django does that automatically.